Recent research has demonstrated that confining stresses applied to the solid framework of coal can reduce its gas sorption capacity by several percent to perhaps several tens of percent. To evaluate the magnitude of this effect more rigorously in relation to predicting in-situ coalbed methane (CBM) content, a better understanding of the effects of stress on methane sorption by coal is needed. In this paper, a previous thermodynamic model for the effects of stress on CO2 sorption by coal is revised and applied to CH4. The revised model predicts that in-situ CBM content is indeed determined not only by the geological factors generally considered, such as coal rank, coal composition, moisture content and temperature, but also by lithostatic or confining stress, which is usually ignored. This prediction is tested by means of experiments performed on a composite cylindrical sample of Brzeszcze 364 high volatile bituminous coal subjected to 10 MPa methane pressure at a temperature of 40 degrees C, varying the hydrostatic stress or confining pressure in the range 11-43 MPa. In these experiments, we determined if CH4 was desorbed as confining pressure was increased by subtracting the poroelastic expulsion of CH4 from the total CH4 expelled, assuming the former to equal the gas volume expelled in control experiments performed using Helium. The experimental results show that the equilibrium sorption capacity for CH4 at 10 MPa gas pressure and 11 MPa confining pressure (1 MPa Terzaghi effective stress) was 0.808 mol/kg(coal), This was reduced by at least similar to 6% by increasing the confining pressure to 43 MPa (33 MPa effective stress), confirming the validity of our model. We apply our model to predict in-situ CBM concentration as a function of coal seam depth for dry, high volatile bituminous coal, assuming a geothermal gradient of 32 degrees C/km. The results indicate a maximum CH4 concentration of similar to 0.76 mol/kgcoal at a burial depth of similar to 900m, which is similar to 3% lower than conventional predictions. This reduction is minor but helps to explain why gas saturation is generally lower than expected from conventional sorption measurements on unconfined coal powders. More importantly, our results confirm that there is an intimate coupling between in-situ stress, strain and sorption in coal that needs to be considered in developing gas-enhanced CBM strategies. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.