Chrome plating is an important emission source of perfluorinated compounds (PFCs) industrial uses in China, where two commercial products potassium 2-(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyloxy) (F-53B) and perfluorooctane sulfonate (PFOS) are applied as mist suppressant, causing non-negligible environmental risk. In this paper, anion-exchange resin IRA67 was evaluated for F-53B and PFOS removal from simulated and actual wastewater. Adsorption kinetics exhibited higher adsorption velocity and capacity of IRA67 for PFOS than F-53B due to their difference in molecular structures. Adsorption isotherms demonstrated the adsorption capacity of F-53B and PFOS on IRA67 was 4.2 mmol/g and 5.5 mmol/g, respectively. Because of the deprotonating of amine groups, solution pH had significant effect on IRA67 at pH>10. The results indicated that besides anion exchange other interactions including hydrophobic interaction and the formation of micelles or hemi-micelles were all involved in adsorption process. Coexisting sulfate and chromate in wastewater decreased adsorption capacities of F-53B and PFOS. The spent resin could be regenerated by the NaCl/NaOH and methanol mixed solution. In the mixed system and actual wastewater IRA67 can simultaneously remove F-53B and PFOS without obvious preference but the removal percent can be affected by competitive effect. (C) 2016 Elsevier B.V. All rights reserved.