The present work shows the results of preparation, characterization, and application of DNA and DNA-PEDOT:PSS coatings as HTM in small dye sensitized solar cells. The samples were analyzed by impedance, UV-Vis and microscopic measurements. The measured ionic conductivities of the DNA membranes were of 2.5x10(-5) and 1.6x10(-3) S/cm at 25 and 75 degrees C, respectively. The addition of PEDOT:PSS to the samples lowered the conductivities to 10(-5)-10(-4) S/cm in the 25-75 degrees C temperature range. The samples of DNA-PEDOT:PSS also showed lower transmittance as compared to pure DNA ones, which was due to their blue coloration. The addition of DNA and DNA-PEDOT:PSS as HTM in DSSC promoted a decrease of the device conversion efficiency, explained as due to the change of TiO2-DNA morphology, increase of the device reflectance, and significant changes in device series and shunt resistances.