Comparative study on degradation of norfloxacin and ciprofloxacin by Ganoderma lucidum JAPC1

Pritha Chakraborty; Jayanthi Abraham

Korean Journal of Chemical Engineering, Vol.34, No.4, 1122-1128, April, 2017

DOI10.1007/s11814-016-0345-6 Export Citation

Comparative study on degradation of norfloxacin and ciprofloxacin by Ganoderma lucidum JAPC1

Pritha Chakraborty, and Jayanthi Abraham^†

Microbial Biotechnology Lab, School of Bioscience and Technology, VIT University, Vellore-632014, Tamil Nadu, India

E-mail:

Indiscriminate use of antibiotics and the rise in drug resistance emphasizes the immediate need for managing pharmaceutical products sensibly. The pharmaceutical products end in wastewater due to the manufacturing process of pharmaceutical industries, misuse of antibiotics and improper disposal of expired drugs, which eventually ends in sewers. In the present study we attempted to degrade fluoroquinolones by the process of mycoremediation. Hospital waste water soil sample was collected and screened for fungi which can tolerate norfloxacin. One fungal isolate was able to withstand 2 g/L of norfloxacin which was chosen for degradation studies. Degradation pattern was checked with HPLC, FTIR and SEM analysis. Kinetics studies were carried out to analyze the degradation pattern. The result confirmed that Ganoderma lucidum JAPC1 strain was capable of degrading norfloxacin successfully but was unable to degrade ciprofloxacin.

Keywords:Ganoderma lucidum;Antibiotics;Biodegradation;HPLC;Kinetic Study

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[1] Pico Y, Andreu V, Anal. Bioanal. Chem.,, 387, 1287 (2007)

[2] Kummerer KA, Al-Ahmad, Mersch-Sundermann V, Chemosphere, 40, 701 (2000)

[3] Giger W, Alder AC, Golet EM, Kohler HPE, McArdell CS, Molnar E, Siegrist H, Suter MJF, Chimia, 57, 485 (2003)

[4] Lindberg RH, Olofsson U, Rendahl P, Johansson MI, Tysklind M, Andersson BA, Environ. Sci. Technol., 40, 1042 (2006)

[5] Duong HA, Pham NH, Nguyen HT, Hoang TT, Pham HV, Pham VC, Berg M, Giger W, Alder AC, Chemosphere, 72, 968 (2008)

[6] Schwartz T, Volkmann H, Kirchen S, Fems Microbiol. Ecol., 57, 158 (2006)

[7] Golet EM, Xifra I, Siegrist H, Giger W, Alder AC, Environ. Sci. Technol., 37, 3243 (2003)

[8] Larsson DGJ, de Pedro C, Paxeus N, J. Hazard. Mater., 148(3), 751 (2007)

[9] Golet EM, Strehler A, Alder AC, Giger W, Anal. Chem., 74, 5455 (2002)

[10] Martinez-Carballo E, Gonzalez-Barreiro C, Scharf S, Gans O, Environ. Pollut., 148, 570 (2007)

[11] Asgher M, Bhatti HN, Ashraf M, Legge RL, Biodegradation, 19, 771 (2008)

[12] Fang QH, Zhong JJ, Biochem. Eng. J., 10, 61 (2002)

[13] Sliva D, Labarrere C, Slivova V, Sedlak M, Lloyd FP, Ho NWY, Biochem. Biophys. Res. Commun., 298(4), 603 (2002)

[14] Fujita R, Liu J, Shimizu K, Konishi F, Noda K, Kumamoto S, Ueda C, Tajiri H, Kaneko S, Suimi Y, Kondo R, J. Ethnopharmacol., 102, 107 (2002)

[15] Perumal K, Murugesan K, Kalaichelvan PT, Indian J. Exp. Biol., 38, 385 (2000)

[16] Turiel EA, Martin E, J. Chromatogr, 1172, 97 (2007)

[17] Kassab NM, Singh AK, Kedor-Hackmam ERM, Santoro MIRM, Braz. J. Pharm. Sci., 41, 507 (2005)

[18] Silambarasan S, Abraham J, PloSone., 8, e77170 (2013)

[19] Sammon C, Yarwood J, Everall N, Stabil., 67, 149 (2000)

[20] Ko EM, Leem YE, Choi HT, Appl. Microbiol. Biotechnol., 57(1-2), 98 (2001)

[21] Silambarasan S, Abraham J, J. Taiwan. Inst. Chem. E., 44, 438 (2013)

[22] Paul T, Miller PL, Strathmann TJ, Environ. Sci. Technol., 41, 4720 (2007)

[23] Wang P, He Y, Huang C, Water Res., 44, 5989 (2010)

[24] Parshikov IA, Heinze TM, Moody JD, Freeman JP, Williams AJ, Sutherland JB, Appl. Microbiol. Biotechnol., 56(3-4), 474 (2001)

[25] Prieto A, Moder M, Rodil R, Adrian L, Marco-Urrea E, Bioresour. Technol., 102(23), 10987 (2011)

[26] Alfarra HY, Hasali NHM, Omar MN, Int. Res. J. Biological Sci., 2, 51 (2013)

[27] Li B, Zhang T, Environ. Sci. Technol., 44, 3468 (2010)