화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Chemical Engineering, Vol.34, No.4, 1149-1158, April, 2017
DOI10.1007/s11814-016-0326-9  Export Citation
Liquid-liquid equilibrium and physical properties of aqueous mixtures of poly(vinyl pyrrolidone) with potassium phosphate at different pH: Experiments and modeling
Abbas Rahmani, Abbas Ali Rostami, Mohsen Pirdashti†, and Poorya Mobalegholeslam1
  • Chemical Engineering Department, Faculty of Engineering, Shomal University, Amol, P. O. Box 731, Iran
  • 1Department of Chemical Engineering, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran
E-mail:
Liquid-liquid equilibrium data for poly vinyl pyrrolidone (PVP) K30+K2HPO4+H2O system were measured at 298.15 K and different pH values (7.54, 8.05, and 9.47). A binodal curve was fitted to the Merchuk equation and the tie line compositions were fitted to both the Othmer-Tobias and Bancroft equations. The refractive indices and densities of several homogeneous binary and ternary solutions used for calibration were also measured within a range of 0-30 mass% of PVP and 0-50 mass% of K2HPO4. Then, the viscosities, densities, electrical conductivities, and refractive indices of binary (PVP K30+water; potassium phosphate+water) and ternary (PVP K30+potassium phosphate+water) systems were measured and correlated at different pH values. The density data showed a linear variation of the polymer and salt mass fractions. The viscosity data of PVP K30 solutions were correlated as a function of the mass fractions by using a nonlinear equation. The effects of the tie line lengths on the densities and viscosities of the aqueous two-phase systems were represented. Also, the modified UNIFAC-NRF is used to calculate the phase equilibria of the mention system. The fitted binary interaction parameters of the model were reported.
Keywords:Liquid-liquid Equilibrium Data;Viscosity;Density;Poly Vinyl Pyrrolidone;Potassium Phosphate;Modified UNIFAC-NRF
  1. Hatti-Kaul R, Methods in Biotechnology: Aqueous Two-Phase Systems: Methods and Protocols, Humana Press Inc., Totowa, NJ (2000).
  2. Raghavarao K, Ravganathan T, Srinivas N, Barhate R, Clean Technol. Environ. Policy., 5, 136 (2003)
  3. Espitia-Saloma E, Vazquez-Villegas P, Aguilar O, Rito-Palomares M, Food Bioprod. Process., 92, 101 (2014)
  4. Luechaua F, Ling TC, Lyddiatt A, Biochem. Eng. J., 50, 122 (2010)
  5. Hu R, Feng X, Chen P, Fu M, Chen H, Guo L, Liu BF, J. Chromatogr. A, 1218, 171 (2011)
  6. Rosa PA, Azevedo AM, Sommerfeld S, Backer W, Aires-Barros MR, Biotechnol. Adv., 29, 559 (2011)
  7. Naganagouda K, Mulimani VH, Process Biochem., 43(11), 1293 (2008)
  8. Bradoo S, Saxena RK, Gupta R, Process Biochem., 35(1), 57 (1999)
  9. Rito-Palomares M, J. Chromatogr. B, 807, 3 (2004)
  10. Asenjo JA, Andrews BA, J. Chromatogr. A, 1238, 1 (2012)
  11. Rodrigues GD, de Lemos LR, da Silva LHM, da Silva MCH, J. Chromatogr. A, 1279, 13 (2013)
  12. Bulgariu L, Bulgariu D, Sep. Purif. Technol., 118, 209 (2013)
  13. Lan JCW, Yeh CY, Wang CC, Yang YH, Wu HS, J. Biosci. Bioeng., 116(4), 499 (2013)
  14. Yan-Min L, Yan-Zhao Y, Xi-Dan Z, Chuan-Bo X, Food Bioprod. Process., 88, 1 (2010)
  15. Rocha MV, Nerli BB, J. Bio. Macromol., 6, 2 (2013)
  16. Buhler V, Excipients for Pharmaceuticals-Povidone, Crospovidone and Copovidone, Springer, Berlin, Heidelberg, New York (2005).
  17. Zafarani-Moattar MT, Zaferanloo A, J. Chem. Thermodyn., 41(7), 864 (2009)
  18. Wang Y, Wu YC, Ni L, Han J, Ma JJ, Hu YT, J. Chem. Eng. Data, 57(11), 3128 (2012)
  19. Zafarani-Moattar MT, Karimi N, Asadzadeh B, J. Mol. Liq., 211, 767 (2015)
  20. Zafarani-Moattar MT, Sadeghi R, Fluid Phase Equilib., 203(1-2), 177 (2002)
  21. Zafarani-Moattar MT, Sadeghi RS, Fluid Phase Equilib., 238(1), 129 (2005)
  22. Salabat A, Moghadasi MA, Zalaghi P, Sadeghi R, J. Chem. Thermodyn., 38(11), 1479 (2006)
  23. Sadeghi R, CALPHAD, 30, 53 (2006)
  24. Sadeghi R, Rafiei HR, Motamedi M, Thermochim. Acta, 451(1-2), 163 (2006)
  25. Zafarani-Moattar MT, Seifi-Aghjekohal P, CALPHAD, 315, 53 (2007)
  26. Fedicheva N, Ninni L, Maurer G, J. Chem. Eng. Data, 52(5), 1858 (2007)
  27. Foroutan M, Zarrabi M, Fluid Phase Equilib., 266(1-2), 164 (2008)
  28. Mokhtarani B, Mortaheb HR, Mafi M, Amini MH, J. Chromatogr. B, 879, 721 (2011)
  29. Baskir JA, Hatton TA, Suter UW, J. Phys. Chem., 93, 2111 (1989)
  30. Renon H, Prausnitz JM, AIChE J., 14, 135 (1968)
  31. Abrams DS, Prausnitz JM, AIChE J., 21, 116 (1975)
  32. Wilson GM, J. Am. Chem. Soc., 86, 127 (1964)
  33. Haghtalab A, Joda M, Fluid Phase Equilib., 278(1-2), 20 (2009)
  34. Haghtalab A, Mokhtarani B, Fluid Phase Equilib., 215, 51 (2004)
  35. Xu X, Madeira PP, Teixeira JA, Macedo EA, Fluid Phase Equilib., 213(1-2), 53 (2003)
  36. Sadeghi R, J. Chem. Thermodyn., 37(1), 55 (2005)
  37. McMillan WG, Mayer JE, J. Chem. Phys., 13, 276 (1945)
  38. Hill TL, J. Chem. Phys., 30, 93 (1959)
  39. Haghtalab A, Mokhtarani B, Maurer G, J. Chem. Eng. Data, 48(5), 1170 (2003)
  40. Perez B, Malpiedi LP, Tubio G, Nerli B, Pessoa PD, J. Chem. Thermodyn., 56, 136 (2013)
  41. Pirdashti M, Movagharnejad K, Mobalegholeslam P, Curteanu S, Leon F, J. Mol. Liq., 223, 903 (2016)
  42. Pitzer KS, J. Phys. Chem., 77, 268 (1973)
  43. Pitzer KS, J. Am. Chem. Soc., 102, 2902 (1980)
  44. Simonson JM, Pitzer KS, J. Phys. Chem., 90, 3005 (1986)
  45. Radfarnia HR, Kontogeorgis GM, Ghotbi C, Taghikhani V, Fluid Phase Equilib., 257(1), 63 (2007)
  46. Pazuki GR, Taghikhani V, Vossoughi M, J. Ind. Eng. Chem., 48, 4109 (2009)
  47. Merchuk JC, Andrews BA, Asenjo JA, J. Chromatogr. B, 711, 258 (1998)
  48. Porto TS, Pessoa-Filho PA, Neto BB, Filho JLL, Converti A, Porto ALF, Jr AP, J. Ind. Microbiol. Biotechnol., 34, 547 (2007)
  49. Shahbazinasab MK, Rahimpour F, J. Chem. Eng. Data, 57(7), 1867 (2012)
  50. Costa ARD, Coimbrab JSDR, Ferreirac LA, Marcos JC, Santos IJB, Marleny DA, Saldana MDA, Food JAC, Bioprod. Process., 95, 118 (2015)
  51. Perumalsamy M, Murugesan T, J. Chem. Eng. Data, 54(4), 1359 (2009)
  52. Waziri SM, Abu-Sharkh BF, Ali SA, Fluid Phase Equilib., 205(2), 275 (2003)
  53. Goldberg RN, J. Phys. Chem. Ref Data, 10, 671 (1981)