The effect of anodic pH on Microbial fuel cells (MFCs) inoculated with marine consortia was investigated to characterize the microbial community adaptation to possible pH environmental changes and to define the pH extreme boundaries beyond which MFCs do not run properly. Tests were conducted in triplicate using different feeding pH values (pH(feed)) ranging from 3 to 13. The MFCs inoculated with marine consortia had a strong self-regulation ability and actively counterbalanced small variations in pH(feed) maintaining the pH inside the anodic chamber (pH(anode)) close to neutrality. As soon as the pH(anode) deviated from neutrality it affected MFCs' performances. Alkaline conditions with pH(anode) values between 8 and 10 corresponded to the formation of a denser biofilm together with the best performance in terms of maximum power density (P-max). Conversely, when the pH(anode) reached values lower than 5.5 or higher than 10, a sharp drop in MFC performances, as well as a decrease of viable population, were observed. Interestingly, the system was able to survive these extreme conditions and restart working effectively when neutrality was reset. The obtained results underline the high adaptability and recovery ability of anodic marine consortia even in extreme conditions, suggesting the employment of this inoculum for MFC applications as biosensors for on-site seawater monitoring or as power supply units to be installed in remote area. (C) 2016 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.