An experimental investigation of a high Reynolds number flow (Re =320 000) of a dilute liquid-solid mixture (<1% by volume) was conducted. The turbulent motion of both the liquid phase (water) and particles (0.5, 1, and 2 mm glass beads) was evaluated in an upward pipe flow using a particle image/tracking velocimetry (PIV/PTV) technique. Results show that the Eulerian mean axial velocity of the glass beads is lower than that of the liquid phase in the central region but higher in the near-wall region. Moreover, the presence of the coarse particles has a negligible effect on the turbulence intensity of the liquid phase. Particles show higher streamwise and radial fluctuations than the liquid-phase at the tested conditions. The profiles of particle concentration across the pipe radius show almost constant concentration in the core of the pipe with a decrease towards the near wall region for 0.5 and 1 mm particles. For the 2 mm particles, a nearly linear concentration gradient from centre to the pipe wall is observed. The results presented here provide new information concerning the effect of a dispersed particulate phase on the turbulence modulation of the liquid carrier phase, especially at high Reynolds numbers. The present study also demonstrates how correlations developed to determine if particles cause turbulence attenuation/augmentation are not applicable for solid-liquid flows at high Reynolds numbers. Finally, the importance of particle-fluid slip velocity on fluid phase turbulence modulation is illustrated. (C) 2016 Elsevier Ltd. All rights reserved.