A multiscale two-phase flow model based on a coupled Eulerian/Lagrangian approach is applied to capture the sheet cavitation formation, development, unsteady breakup, and bubble cloud shedding on a hydrofoil. No assumptions are needed on mass transfer. Instead natural free field nuclei and solid boundary nucleation are modelled and enable capture of the sheet and cloud dynamics. The multiscale model includes a micro-scale model for tracking the bubbles, a macro-scale model for describing large cavity dynamics, and a transition scheme to bridge the micro and macro scales. With this multiscale model small nuclei are seen to grow into large bubbles, which eventually merge to form a large scale sheet cavity. A reentrant jet forms under the sheet cavity, travels upstream, and breaks the cavity, resulting in the emission of high pressure peaks as the broken pockets shrink and collapse while travelling downstream. The method is validated on a 2D NACA0015 foil and is shown to be in good agreement with published experimental measurements in terms of sheet cavity lengths and shedding frequencies. Sensitivity assessment of the model parameters and 3D effects on the predicted major cavity dynamics are also discussed. (C) 2017 Elsevier Ltd. All rights reserved.