Biophotovoltaic devices modified with immobilized polymeric osmium/azine redox-mediators exhibited a considerable electrical output enhancement (64/43-fold under light/dark conditions, respectively). More importantly, the systems exhibited uninterrupted current generation at same magnitude levels during day/night cycles, paving the way toward solar energy conversion bio-panels that will not require energy storage peripherals. (C) The Author(s) 2016. Published by ECS. All rights reserved.