화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Polymer(Korea), Vol.41, No.3, 404-412, May, 2017
DOI10.7317/pk.2017.41.3.404  Export Citation
Geranium Wilfordii Maxim이 봉입된 마이크로캡슐의 제조와 체외방출 성능
Preparation and In-Vitro Release Performance of Geranium Wilfordii Maxim Filled Biodegradable Microcapsules
Mengxuan Li, Rui Wang†, and Xing Liu
  • School of Textiles, Tianjin Polytechnic University, Tianjin 300387, China
E-mail:
Encapsulation of Geranium wilfordii Maxim (GWM) into polyvinyl alcohol (PVA) biodegradable microcapsules was performed using the interfacial polymerization method. The optimum synthesis conditions including the core/shell ratio and the emulsifier concentration were explored. The fabricated microcapsules were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The in-vitro release behaviour of the GWM microcapsules was studied by ultraviolet-visible spectroscopy (UV-VIS). The results show that when the core/shell ratio was 1:1 and the emulsifier concentration was 5%, the GWM microcapsules sizes have a normal distribution with a mean diameter of 23.94 μm. FTIR results show that the GWM was successfully encapsulated by the PVA polymer. TG results indicate that the GWM microcapsules are stable below 300 °C. Moreover, the release from the GWM microcapsules occurs according to a non-Fickian diffusion model.
Keywords:traditional Chinese medicine extractive;microcapsule;slow-release;interfacial polymerization
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