For NOx removal from the exhaust gases of municipal solid waste (MSW) incinerators by selective catalytic reduction (SCR) technology, a suitable SCR catalyst which is active at low temperatures and robust to the presence of alkali metals and SO2 is highly desired. In this contribution, we report the successful fabrication of a highly dispersed CuyAlO(x) (y = 24) mixed oxides for NH3-SCR catalyst using high surface area, flower-like highly dispersed AMO-Cu-Al-CO3 LDHs precursors. The influence of the Cu/Al ratio (2, 3, 4, and 5), calcination temperature (400, 500, 600, and 700 degrees C), and testing temperature (150, 200, 250, and 300 degrees C) on the activity of the CuyAlOx mixed oxide catalysts were systematically investigated. Among all samples, Cu(4)AlOx showed the highest NOx conversion of 91.1% at 200 degrees C. After being thermally treated at 700 degrees C, the NOx conversion of Cu(4)AlOx was still as high as 84.7%, which is much higher than that of the control catalyst 10 wt% CuO/gamma-Al2O3 (57.5%). XRD and HR-TEM analyses suggested that the highly dispersed CuO nanoparticles are the active species for the SCR reaction. The catalytic De-NOx performance of Cu(4)AlOx in the presence of alkali metals (K and Na) and SO2 was also studied. In the presence of 50 ppm SO2, the NOx conversion of Cu(4)AlOx (78.4%) was much higher than that of CuO/gamma-Al2O3 (48%). The selectivity of NOx conversion to N-2 and resistance to H2O (and co-existence of H2O and SO2) for Cu(4)AlOx catalyst were also evaluated. In all, we have demonstrated that the newly obtained Cu(4)AlOx catalyst not only possesses higher thermal stability and higher low temperature (150-250 degrees C) catalytic activity, but also has much better alkali metal (K and Na), SO2, and H2O resistance than a conventional CuO/gamma-Al2O3 catalyst. (C) 2017 Elsevier B.V. All rights reserved.