Chemistry Letters, Vol.46, No.8, 1090-1092, 2017
Electronic and Steric Effects of Cyclic Amino Substituents of Luciferin Analogues on a Firefly Luciferin-Luciferase Reaction
Bioluminescent and spectroscopic properties of luciferin analogues with cyclic amino substituents (1-pyrrolidinyl, piperidino, 1-azepanyl, and morpholino groups) at the 6' position were investigated by comparing with those of 6'-dimethylaminoluciferin, to provide information on spatial and molecular environmental properties of the active site in Photinus pyralis luciferase.