This work presents a systematic evaluation of the effect of dissimilar charging / discharging temperatures on the long-term performance of lithium iron phosphate / graphite based cells by using multi-factor analysis of variance. Specifically, the degradation of prototype pouch cells is presented in a range of charging and discharging temperatures from -20 degrees C to +30 degrees C, counting a total of 10 temperature combinations. In this manner, not only the effect of charging and discharging temperatures was analyzed, but also the correlations between them. Fitting of the data showed a quadratic relationship of degradation rate with charging temperature, a linear relationship with discharging temperature and a correlation between charging and discharging temperature. Cycling at the charge/discharge temperatures (+30 degrees C, -5 degrees C) produced the highest degradation rate, whereas cycling in the range from -20 degrees C to +15 degrees C, in various charge/discharge temperature combinations, created almost no degradation. It was also found that when Tc congruent to 15 degrees C the degradation rate is independent of Td. When Tc < +15 degrees C, the higher degradation occurs at higher Td and at Tc > +15 degrees C lower degradation occurs at higher Td. (C) 2017 The Author(s). Published by Elsevier Ltd.