The efficiency of electrostatic coalescence coupled with microwave heating in separation of water-in-oil (W/O) model emulsions was evaluated. A series of experiments were performed in a continuous pilot plant where a W/O emulsion can be treated by application of electric field, microwave heating, conventional heating, or a combination of these techniques. The separation efficiencies in the two process configurations were evaluated by measuring the water content of treated model emulsion. The combination of electrocoalescence and microwave showed better separation results, in comparison to conventional heating combination with electrocoalescence. The influence of four operational variables on the water contents of the treated emulsions were studied: salt concentration, flow rate, the electric field between electrodes, and water cut at the inlet were evaluated. It was observed that a lower flow rate (higher residence time) helped in reducing the final water content and that a higher salt content resulted in worse separation efficiency. The microwave heating showed to be an attractive alternative to conventional heating, particularly when the electrocoalescer is under operational stress.