An electrochemical and statistical view of methanol extract of Luffa aegyptiaca leaves (MLA) on the corrosion inhibition of mild steel (MS) in 0.5M H2SO4 medium were investigated by potentiodynamic polarisation and electrochemical impedance spectroscopy. Polarization studies showed that the MLA acts as mixed type inhibitor with predominant cathodic behaviour. The percentage inhibition efficiency was found to increase with MLA concentration and decreased with the temperature. Thermodynamic parameter such as free energy value was negative, that indicates spontaneous adsorption of inhibitor on MS surface. Adsorption of MLA was found to obey Langmuir isotherm. The analysis of variance studies showed that the inhibition efficiencies calculated from the different electrochemical parameters are statistically significant. Surface studies were performed by Fourier transform infrared spectroscopy and atomic force microscopy.