The speed of sound of hydrofluoroether fluid HFE-7500 has been measured at pressures up to 100 MPa along isotherms ranging from (293.15 to 353.15).K. The measurements were carried out using a pulse echo technique operating at 3 MHz. Additional high pressure density data were measured up to 140 MPa with temperatures from (293.15 to 393.15)K in order to evaluate isentropic compressibility using speed of sound measurements. A correlation was then proposed to describe both density and speed of sound within their estimated uncertainties and used to evaluate the density and its derivatives. (C) 2017 Elsevier Ltd.