Carbon nanotube-reinforced silicon carbide composites (CNT/SiC) produced by direct infiltration of matrix into a porous CNT arrays have been demonstrated to possess a unique microstructure and excellent micro-mechanical properties. However, the thickness of the array preforms is usually very small, typically less than 2 mm. Therefore, fabrication of macroscopic CNT/SiC composites by chemical vapor infiltration (CVI) process requires that the nanoscale fillers could form macroscopic architectures with an open pore network. Here, this study reports an experimental strategy for the fabrication of SiC matrix composites reinforced by CNT based on an ice-segregation-induced self-assembly (ISISA) technique. Macroscopic CNT aerogel with well-defined macroporous network was produced by ISISA technique and was subsequently infiltrated by SiC in a CVI reactor. After five CVI cycles, the porosity of as-fabricated composites was 11.6 +/- 0.3% and the machined specimens exhibited lamellar structure with parallel lamellaes intersected at discrete angles. By observed, there are in fact five different representative anisotropic macrostructures, the compressive strengths of these five different loading modes with respect to lamella orientation were 933 +/- 55, 619 +/- 34, 200 +/- 45, 199 +/- 21, and 297 +/- 41 MPa, respectively, and the failure mechanisms were attributed to the anisotropic nature of the macrostructures. Energy dissipation toughening mechanism at the nanoscale such as CNT pull-out was observed and the phase composition of the fabricated materials included -SiC, CNT, and SiO2.