Organic semiconducting/ferroelectric blend films attracted much attention due to their cross-talk-free resistive property. Blend films were fabricated from the co-dissolved solution of both semiconducting and ferroelectric components. Spinodal decomposition induced phase separation which was the key structure for determination of resistive property in such blend films. However, till now only seldom work concerned the theoretic studies on phase separation process in semiconducting/ferroelectric blend systems. Here we reported our work on dissipative particle dynamics simulation of phase separation in such blend system. Phase separation morphology was evaluated as a function of the blending ratio of both components. Quantitative analysis method was developed for direct comparison of the domain sizes of semiconducting phase obtained from both simulated and experimental observations. Simulation work was well consistent with direct experimental results. (C) 2017 Elsevier Ltd. All rights reserved.