Hypericin, Hypocrellin, and Model Compounds - Primary Photoprocesses of Light-Induced Antiviral Agents

English DS; Das K; Zenner JM; Zhang W; Kraus GA; Larock RC; Petrick JW

Journal of Physical Chemistry A, Vol.101, No.18, 3235-3240, 1997

English DS, Das K, Zenner JM, Zhang W, Kraus GA, Larock RC, Petrick JW

The excited-state photophysics of the light-induced antiviral agents hypericin and hypocrellin are compared with those of the hexa- and tetramethoxy analogues of hypericin. The results are consistent with the interpretation of the primary photoprocess in hypericin and hypocrellin as that of excited-state intramolecular proton or atom transfer.

Keywords:STATE PROTON-TRANSFER;3-HYDROXYFLAVONE;SOLVENT;OXYGEN;PHOTOSENSITIZATION;ACIDIFICATION;KINETICS