Calculations of Te-125 nuclear magnetic resonance chemical shifts are reported for a number of organic, inorganic, and organometallic tellurium-containing complexes. The selected systems cover almost the complete spectrum of known Te-125 chemical shifts with a range of about 3000 ppm. The calculations are based on density functional theory (DFT) and gauge-including atomic orbitals (GIAO’s). It is concluded that the DFT-GIAO method is able to reproduce the observed trends in Te-125 chemical shifts for organic, inorganic, and organometallic compounds.