Multicomponent reaction of dimedone or 1,3-dimethylbarbituric acid and malononitrile with a series of bis (indoline-2,3-diones) afforded the corresponding bis(2-amino-7,7-dimethy1-2 ',5-dioxo-5,6,7,8-tetrahydrospiro [chromene4,3'-indoline]-3-carbonitrile) and bis(7'-amino-1',3'-dimethy1-2,2',4'-trioxo-1',2',3',4'-tetrahydrospiro[indoline-3,5'-pyrano [2,3-d]pyrimidine]-6'-carbonitrile) derivatives in good to excellent yield.