Flower-shaped microarchitectures of V2O5:Fe3+ were synthesized via an oxalic acid -assisted precipitation in a high-gravity rotating packed bed along with post hydrothermal and calcination process. The rotating packed bed (RPB) was used to create a high-gravity environment for V2O5:Fe3+ nanoparticles precipitation. Three dimensional (3D) micro-flowers were then formed due to the growth of V2O5:Fe3+ nanoplates and self-assembly during the hydrothermal and calcination process. As a result of the process intensification by high gravity technology, the V2O5:Fe3+ microarchitectures obtained by RPB were more uniform than those obtained in stirred tank, exhibiting excellent performance at high current density as cathode materials for lithium ion batteries (LIBs). This work put forward a novel method to control the crystal form of cathode materials for LIBs.