Kinetic analysis was investigated using the deactivation kinetics model, where the reaction order of each species based on the experimental data was estimated for H2S removal over mesoporous Cu-Mn mixed oxide/SBA-15 and La-Mn mixed oxide/KIT-6 sorbents during hot coal gas desulfurization in a fixed-bed reactor. The reaction orders, rate constants, apparent activation energy (E-a), and deactivation energy (E-d) were calculated as the kinetic parameters. The calculated reaction orders, alpha, beta, and gamma, were 1, 1, and 1 for Cu-Mn mixed oxide/SBA-15 and 0.6, 1.2, and 1 for La-Mn mixed oxide/KIT-6. The obtained E-a and E-d for Cu1Mn9 mixed oxide/SBA-15 were 33.02 and 46.34 kJ mol(-1) and for La3Mn97 mixed oxide/KIT-6 were 48.98 and 56.10 kJ mol(-1), respectively. This model offered the H2S breakthrough curves for the whole duration of the desulfurization reaction, with errors less than 5% between calculated and experimental data.