An Artificial Neural Network model is proposed for the calculation and prediction of the surface tension of alcohols. A total amount of 4316 data for 147 alcohols was used for training, validating and testing the network model. After considering different architectures, the one giving better results includes an input layer that uses four independent variables (temperature, critical point temperature, critical density, and radius of gyration), two hidden layers with 21 neurons each one, and one neuron in the output layer was found to give the best results. Overall mean absolute percentage deviation of 1.04% was found, whereas models based on corresponding-states principle give mean deviations higher than 11.3%. (C) 2017 Elsevier B.V. All rights reserved.