Water-washed cottonseed meal (WCSM) has been shown as apromising bio-based wood adhesive. In this work, we tested the bonding strength of WCSM slurries with high solid contents and low press temperatures per industrial input for non-structural applications as European Standard Class D1 wood adhesives. Increasing the WCSM content from 11 to 20% and 30% did not substantially change the adhesive strength but increased the viscosity of WCSM slurries dramatically. The shear strength at break of the maple wood pairs bonded at 40 and 60 degrees C was lower than that of maple pairs bonded at 100 degrees C. However, the shear strength of the pairs bonded at lower temperatures (40 and 60 degrees C) could be improved by extending the press time from 20 to 120 min. Addition of citric acid (CA) improved the viscosity of the WCSM adhesive at 20% solid content, but lowered the adhesive strength. The addition of denaturing reagent sodium dodecyl sulfate (SDS) showed reverse impacts on the adhesive strength and viscosity, compared to CA addition. Based on these observations, eight adhesive slurries were formulated with 20 and 30% of WCSM, 3% of CA or SDS, or 9.6% or 19.1% of denaturing reagent guanidine hydrochloride (GdmCl), and their bonding strengths were tested. These formulations could be used as the basis for developing low temperature WCSM-based wood adhesives to meet the criteria of both operational flowability and shear strength of the domestic furniture and small utensils niche markets for forest products.