Published data on the influence of sulfur and its compounds on the ecological properties and performance characteristics of diesel fuels have been analyzed. The main characteristics of depressant, antiwear, and antioxidant additives to modern hydrotreated diesel fuels with low and ultralow sulfur content have been considered. A special emphasis is made on the additives based on synthetic and natural high-molecularweight compounds, including complex multifunctional broad-spectrum additives for clean diesel fuels, conforming to the European requirements and quality standards.