The relationship between the wind resource in Southern South America (SSA) and the Antarctic Oscillation (AAO) and El Nino/Southern Oscillation (ENSO) is analyzed in this paper. Daily, monthly, seasonal and annual correlations were calculated between wind speeds at 50 m height derived from MERRA reanalysis and the indices of the mentioned climate drivers. Our results shows that the AAO exerts a significant control over wind speeds on inter annual and seasonal timescales. This relation is stronger during spring and summer, with negative correlations over northern Patagonia, the Argentine and Uruguayan Pampas and Paraguay. ENSO shows weaker relations with wind speeds, mainly on the monthly timescale, with negative correlations over Central Argentina; and during spring, with negative correlations over Southern Patagonia. The relations between MO and wind speeds are relevant in the context of projected climate changes in the region over the next decades. ENSO might be used as a predictor of wind energy production over monthly and seasonal timescales (mainly during spring) in central Chile and Argentina, and Southern Patagonia. (C) 2017 Elsevier Ltd. All rights reserved.