Granule-shaped Ce-doped TiO2/diatomite (GCTD) hybrid was prepared via sol-gel method. The physicochemical properties of this hybrid were characterized by various analytical methods. As carrier, diatomite was conducive to the dispersion of TiO2 nanoparticles, hindering their agglomeration process. Compared to TiO2, GCTD showed visible-light-driven photoactivity, which was evaluated by the degradation of oxytetracycline (OTC) and disinfection of three bacteria (Escherichia coli, Staphylococcus aureus and Klebsiella pneumonia) under visible light. The porous diatomite enhanced the photoactivity of TiO2 via the adsorption towards target pollutants. The reusability experiment was conducted for 5 times, and the results showed that GCTD exhibited good photo-stability and reusability. (C) 2017 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.