The Chemical Looping with Oxygen Uncoupling (CLOU) process is a form of Chemical Looping Combustion (CLC) technology that enables the combustion of solid fuels by means of oxygen carriers that release gaseous oxygen in the fuel reactor, i.e. with oxygen uncoupling capability. In recent years, tests have found several Cu based, Mn-based and mixed oxide oxygen carriers with suitable properties for the CLOU process. Among them, Cu-Mn mixed oxides show high reactivity and high O-2 equilibrium concentration at temperatures of interest for coal combustion. In this work, proof of concept was demonstrated by burning coal with Cu-Mn mixed oxides in a 1.5 kWth CLOU unit for the first time. The effect of fuel reactor temperature, solids circulation flow, fluidization agent in the fuel reactor (inert N-2 or steam as gasifying agent), and excess air in the air reactor on combustion efficiency and CO2 capture rate was analysed. The results showed that high combustion efficiency and CO2 capture are feasible using this material at relatively low fuel reactor operating temperatures. Therefore, the developed Cu-Mn mixed oxide was a suitable material for use as an oxygen carrier for the CLOU combustion of solid fuels. Optimum operating conditions were determined for this oxygen carrier with regard to the oxygen circulation rate and air reactor conditions for the regeneration of the oxygen carrier.