The reactivity of Bi0.5Sr0.5MnO3, Bi0.5Sr0.5Mn0.7Cu0.3O3, Bi0.5Sr0.5Mn0.7Ni0.3O3, La0.5Sr0.5Mn0.7Cu0.3O3 and La0.5Sr0.5Mn0.7Ni0.3O3 in ethanol steam reforming was studied. Different steam to carbon ratios have been tested (therefore referred as S/C = 1.5, and S/C = 6). The effect of an ad hoc reduction pre-treatment was also investigated. Ethanol conversion is highest in La0.5Sr0.5Mn0.7Ni0.3O3 and significant selectivity toward hydrogen and CO2 is observed. The reduction pre-treatment is more effective on nickel containing catalysts, enhancing both ethanol conversion and H-2 and CO2 selectivity.