This work presents a study of the electronic transport properties of PbSe pellets fabricated starting of PbSe nanostructures that exhibited a flake-like 2D morphology, which were synthesized by the co-precipitation method. Seebeck coefficient measurements revealed that the PbSe sample displays n-type conductivity, a maximum Seebeck coefficient of -512.6 mu V/K around 380 K, and that the carriers scattering is dominated by acoustic and optical phonons. The Fermi level dependence on the temperature and the band gap energy are also reported. Interestingly, size-dependent confinement effects due probably to the reminiscent PbSe 2D character could be evidenced. (c) 2017 Elsevier B.V. All rights reserved.