This work shows a study of the reactivity of twelve different types of soot with either NO2 or O-2 under reacting conditions typically present in diesel particulate filters (DPFs). The soot samples were obtained from the combustion of four conventional and alternative fuels (diesel, biodiesel and two paraffinic fuels) in a diesel engine bench operated under three different engine operation modes: a typical urban-driving mode and two variations to this mode to assess the effect of the injection settings. The main objective of the work is to relate the oxidative reactivity of the soot to the nature and the origin of each sample. The possible simultaneous elimination of soot and NOx at typical diesel exhaust conditions is examined, as well. The reactivity tests were performed in a laboratory quartz gas flow reactor, discontinuous for the solid. The soot-NO2 interaction was studied with 200 ppm of NO2 at 500 degrees C and the soot-O-2 interaction was studied with 5% O-2 at 500 degrees C and 600 degrees C. The experimental results were used to determine the time needed for the complete conversion of carbon (t) through the use of the equations of the Shrinking Core Model for solid-gas reactions with decreasing size particle and chemical reaction control. In general, the t values show that the diesel fuel generates a less reactive soot than biodiesel or the alternative paraffinic fuels. In addition, increasing the injection pressure or adding a post-injection to the original injection strategy generates a more reactive soot. These findings point out that there is potential to achieve efficient regeneration processes in DPFs through other fuels than conventional ones and via engine calibration.