Strontium plays important physicochemical and biological roles in the applications of bone repair materials. The available methods of Sr doping in bone cements were believed to make a key effect on the biodegradation and Sr ion release behaviors of cements. In this work, Sr-doped octacalcium phosphate (Sr-OCP), Sr-doped -tricalcium phosphate (Sr--TCP), SrCO3, and SrCl2 with different actual availability of Sr2+ were imported into -TCP bone cements, and their effects on the biodegradation and ions release of cements were comparatively investigated. Incorporation of different Sr carriers had led to distinct hydration morphologies, crystal evolutions, degradation rates, and microenvironments of bone cements during their invitro biodegradation. Compared with other Sr carriers, Sr-OCP facilitated the hydration reaction of -TCP, which induced the enhanced degradation and Sr ion release behaviors. In conclusion, Sr-OCP was supposed to be a more potential Sr carrier applied in the synthesis of biodegradable Sr-doped calcium phosphate bone cements.