In this study, we reported an optimized facile method to synthesize ZnO particles of three kinds of morphologies, flower-like, rod-like and sphere. Although ZnO grew along the a- and c-axes, however, the anisotropic crystal growth mechanism of ZnO particles was investigated by the ratio of precursor and temperature of the reaction. The characterizations of three ZnO particles were measured by Field emission scanning electron microscopy, Fourier-transform infrared spectroscopy and X-ray diffraction. In addition, ZnO with three shapes was fixed on gold-printed circuit board to detect their electrochemistry property in a 3% H2O2/phosphate buffer, while ZnO/GO (graphene oxide) composite was obtained by organic linking which showed the different electrochemical results compare to that of ZnO. electron-transfer distance and speed have been changed between the products and support due to the combination of ZnO and GO. The exploration of ZnO of different shape and ZnO/GO composites on their features and properties would provide significant evidence for their application as sensors in extensive fields. (C) 2017 Elsevier B.V. All rights reserved.