A fast, highly sensitive and selective non-enzymatic electrochemical glucose sensor based on graphene sheet/ graphene nanoribbon/nickel nanoparticles (GS/GNR/Ni) hybrid material modified electrode was fabricated. The hybrid material was synthesized via facile in-situ chemical reduction and characterized by X-ray diffraction, transmission electron microscopy, Raman spectroscopy, cyclic voltammetry and electrochemical impedance spectroscopy. The GS/GNR/Ni/GCE showed high electrochemical activity towards the oxidation of glucose in a 0.1 M NaOH solution. At an applied potential of +0.5 V, it displayed wide linear amperometric response towards glucose from the range of 5 nM-5 mM, with a detection limit of 2.5 nM and sensitivity of 2.3 mA/mM cm(2). Moreover, the modified electrode was relatively insensitive to commonly interfering species such as dopamine, ascorbic acid, sucrose, uric acid and Cl- ions. The fabricated sensor with better reproducibility, good long term stability, makes it a promising electrode for the development of effective glucose sensor.