화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.59, 320-327, March, 2018
DOI10.1016/j.jiec.2017.10.038  Export Citation
Application of modified cloud point extraction method for the chromium speciation in artificial saliva extracts of different snuff products
Asma Akhtar†, Tasneem Gul Kazi, Hassan Imran Afridi, Mustafa Khan, Muhammad Bilal, and Noman Khan
  • National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan
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A modified cloud point extraction method (m-CPE) was developed for the speciation of chromium species (Cr3+ and Cr6+) in artificial saliva extracts (ASE) of snuff products. In this method, Cr3+ was complexed with 8-hydroxyquinoline, which was trapped in nonionic surfactant (Triton X-114), prior to analyzed by electrothermal atomic absorption spectrometer (ETAAS). Whereas, the total extractable Cr was determined by reducing Cr6+ to Cr3+ using Na2SO3 as a reducing reagent. Several parameters were optimized for the developed m-CPE. Under the most favorable conditions, enrichment factor, enhancement factor and limit of detection for the proposed method were 60, 134 and 0.04 mg L-1, respectively having relative standard deviation <5%. Health risks associated with the intake of total Cr in snuff products was also assessed. Estimated daily intake of Cr via sniffing 10 g/day of dry and moist snuff products was found below the maximum tolerable daily intake whereas the calculated risk for cancer due to Cr was observed in the acceptable range of 10 E-6.E-4.
Keywords:Dry and moist snuff;Modified cloud point extraction method;Risk assessment;Electrothermal atomic absorption;spectrometer
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