Tramadol hydrochloride delivery by regenerated cellulose nanofiber-TiO2-ZnO composites

Gabriel Ademola Olatunji; Adeola Tawakalt Kola-Mustapha; Oluwaseyi Damilare Saliu; Aderemi Babatunde Alabi; Oluwafemi Idowu Abiodun; Nike Olatayo Obisesan

Korean Journal of Chemical Engineering, Vol.35, No.3, 784-791, March, 2018

DOI10.1007/s11814-017-0314-8 Export Citation

Tramadol hydrochloride delivery by regenerated cellulose nanofiber-TiO2-ZnO composites

Gabriel Ademola Olatunji, Adeola Tawakalt Kola-Mustapha¹, Oluwaseyi Damilare Saliu^†, Aderemi Babatunde Alabi², Oluwafemi Idowu Abiodun, and Nike Olatayo Obisesan

Department of Industrial Chemistry, University of Ilorin, Ilorin, Nigeria
¹Department of Pharmaceutics and Industrial Pharmacy, University of Ilorin, Ilorin, Nigeria
²Department of Physics, University of Ilorin, Ilorin, Nigeria

E-mail:

The present work focuses on the development and investigation of new composite materials based on regenerated nanocellulose, titanium oxide (TiO2) and zinc oxide (ZnO) with potentials for drug delivery applications. The new composite was developed using dispersion method. The physicochemical properties of the composites were extensively evaluated using scanning electron microscopy (SEM), X-ray diffraction (XRD), particle size analyzer and Fourier transform infrared spectroscopy (FTIR). The presence of O-H, C-H, C-O-C, Ti-O, Zn-O stretch and bend was confirmed using the FTIR, while the SEM revealed the TiO2 and ZnO immobilized on the surface of stiff and rod-like strands of regenerated nanocellulose. The XRD showed characteristic peaks at 2θ of 16.6°, 22.7°, 34.4° for nanocellulose, 17.5°, 24.5°, 32° for ZnO and 25.4°, 38°, 48.3°, 53.8° for TiO2. As the amount of the metal oxides in the composite increased, notable increase in physicochemical properties and morphology for drug delivery purpose was observed. The cumulative drug release profiles of the regenerated nanocellulose composites on tramadol hydrochloride were subjected to zero order, first-order, Higuchi and Korsmeyer-Peppas plots, and fitted most for Korsmeyer-Peppas with R2 and n value from 0.9831 to 0.9941 and 0.4188 to 0.9704, respectively.

Keywords:Regenerated;Nanocellulose;Zinc Oxide;Titanium Oxide;Composite

[References]

Wang H, Lin T, Zhu G, Yin H, Lu X, Li Y, Huang F, Catal. Commun., 60, 55 (2015)
Jones N, Ray B, Ranjit KT, Manna AC, Microbiol. Lett., 279(1), 71 (2008)
Djaoued Y, Balaji S, Beaudoin N, J. Sol-Gel Sci. Technol., 65(3), 374 (2013)
Tobaldi DM, Pullar RC, Gualtieri AF, Seabra MP, Labrincha JA, Acta Mater., 61(15), 5571 (2013)
Wang H, Lin T, Zhu G, Yin H, Lu X, Li Y, Huang F, Catal. Commun., 60, 55 (2015)
Schutz C, Sort J, Bacsik Z, Oliynyk V, Pellicer E, Nanoparticle Hybrids, 7, e45828 (2012)
Azizi S, Ahmad MB, Hussein MZ, Ibrahim NA, Molecules, 18, 6269 (2013)
Snyder A, Bo Z, Moon R, Rochet J, Stanciu L, J. Colloid Interface Sci., 399, 92 (2012)
Tiwari SB, Murthy TK, Pai MR, Mehta PR, Chowdary PB, AAPS PharmSciTech., 4(3), 18 (2003)
Mohan A, Vaishali T, American J. Adv. Drug Delivery, 1(4), 435 (2013)
Chauhan PY, Sapkal RS, Sapkal VS, Zamre GS, Int. J. Chem. Sci., 7(2), 681 (2009)
Zhang Y, Liu C, Wang S, Wu Y, Meng Y, Cui J, Zhou Z, Wood Fiber Sci., 47(3), 1 (2015)
Zhang L, Jiang Y, Ding Y, Daskalakis N, Jeuken L, Povey M, O’Neill AJ, York DW, J. Nanopart. Res., 12(5), 1625 (2009)
Kianfar F, Antonijevic M, Chowdhry B, Boateng JS, Colloids Surf. B: Biointerfaces, 103, 99 (2013)
Straccia MC, Ayal GG, Romano I, Oliva A, Laurienzo P, Marine Drugs, 13, 2890 (2015)
Fentie M, Belete A, Mariam TG, J. Nanosci. Nanotechnol., 6, 262 (2015)
Sivakumar T, Venkatesan P, Manavalan R, Valliappan K, J. Basic Clinical Pharmacy, 69(1), 154 (2007)
Reddy AS, Sailaja AK, World J. Pharmacy Pharmaceutical Sci,, 3(6), 1781 (2014)
Sudhakar P, Bhagyamma S, Siraj S, Sekharnath K, Rao K, Subha M, J. Appl. Pharm. Sci., 5(2), 51 (2015)
Kianfar F, Antonijevic M, Chowdhry B, Boateng JS, Colloids Surf. B: Biointerfaces, 103, 99 (2013)
Straccia MC, Ayal GG, Romano I, Oliva A, Laurienzo P, Marine Drugs., 13, 2890 (2015)
Garud N, Garud A, Tropical J. Pharmaceutical Res., 11(4), 577 (2012)
Pandey M, Amin MCIM, Ahmad N, Abeer MM, Int. J. Polym. Sci., 2013, 1 (2013)
Ibrahim MM, Tamer Y, Fahmy A, Salaheldin EI, Mobarak F, Youssef MA, Mabrook MR, J. American Sci., 10(12), 108 (2014)
Rodnyi PA, Khodyuk IV, Optics Spectroscopy, 111(5), 776 (2011)
Soosen SM, Lekshmi B, George KC, SB Academic Review, 16(1&2), 57 (2009)
Kumar H, Rani R, Int. Lett. Chem., Phys. Astronomy, 14, 26 (2013)
Janotti A, Van de Walle CG, Reports on Progress in Physics, 72(126501), 29 (2009)
Qin L, Shing C, Sawyer S, Dutta PS, Optical Mater., 33, 359 (2011)
Pugachevskii MA, Technical Phys. Lett., 39(1), 36 (2013)
Hammad TM, Salem JK, Harrison RG, Rev. Adv. Mater Sci., 22, 74 (2009)
Egerton TA, Molecules, 19, 18192 (2011)
Ano LMM, Stork CJ, Li YY, J. Cosmetic Dermatology, 9, 276 (2010)
Salas C, Nypelo T, Rodriguez-Abreu C, Carrillo C, Rojas OJ, Curr. Opin. Colloid Interface Sci., 19, 383 (2014)
Pal SB, Dutta J, Nanoscience Nanotechnology-Asia, 2, 90 (2012)
Yang HY, Zhu SK, Pan N, J. Appl. Polym. Sci., 92(5), 3201 (2004)
Nazir MS, Wahjoedi BA, Yussof AW, Abdulah MA, Bioresources, 8(2), 2161 (2013)
Alemdar A, Sain M, Bioresour. Technol., 99(6), 1664 (2008)
Saelee K, Yingkamhaeng N, Nimchua T, Sukyai P, The 26th Annual meeting of the Thai Society for Biotechnology and International Conference (2014).
Morawski AW, Kusiak-Nejman E, Przepiorski J, Kordala R, Pernak J, Cellulose, 20, 1293 (2013)
Galkina OL, Sycheva A, Blagodatskiy A, Kaptay G, Katanaev VL, Seisenbaeva GA, Kessler VG, Agafonov AV, J. Surf. Coat. Technol., 253, 171 (2014)
Yu Q, Wu P, Li L, Liu T, Zhao L, Green Chem., 10, 1061 (2008)

[1] Wang H, Lin T, Zhu G, Yin H, Lu X, Li Y, Huang F, Catal. Commun., 60, 55 (2015)

[2] Jones N, Ray B, Ranjit KT, Manna AC, Microbiol. Lett., 279(1), 71 (2008)

[3] Djaoued Y, Balaji S, Beaudoin N, J. Sol-Gel Sci. Technol., 65(3), 374 (2013)

[4] Tobaldi DM, Pullar RC, Gualtieri AF, Seabra MP, Labrincha JA, Acta Mater., 61(15), 5571 (2013)

[5] Wang H, Lin T, Zhu G, Yin H, Lu X, Li Y, Huang F, Catal. Commun., 60, 55 (2015)

[6] Schutz C, Sort J, Bacsik Z, Oliynyk V, Pellicer E, Nanoparticle Hybrids, 7, e45828 (2012)

[7] Azizi S, Ahmad MB, Hussein MZ, Ibrahim NA, Molecules, 18, 6269 (2013)

[8] Snyder A, Bo Z, Moon R, Rochet J, Stanciu L, J. Colloid Interface Sci., 399, 92 (2012)

[9] Tiwari SB, Murthy TK, Pai MR, Mehta PR, Chowdary PB, AAPS PharmSciTech., 4(3), 18 (2003)

[10] Mohan A, Vaishali T, American J. Adv. Drug Delivery, 1(4), 435 (2013)

[11] Chauhan PY, Sapkal RS, Sapkal VS, Zamre GS, Int. J. Chem. Sci., 7(2), 681 (2009)

[12] Zhang Y, Liu C, Wang S, Wu Y, Meng Y, Cui J, Zhou Z, Wood Fiber Sci., 47(3), 1 (2015)

[13] Zhang L, Jiang Y, Ding Y, Daskalakis N, Jeuken L, Povey M, O’Neill AJ, York DW, J. Nanopart. Res., 12(5), 1625 (2009)

[14] Kianfar F, Antonijevic M, Chowdhry B, Boateng JS, Colloids Surf. B: Biointerfaces, 103, 99 (2013)

[15] Straccia MC, Ayal GG, Romano I, Oliva A, Laurienzo P, Marine Drugs, 13, 2890 (2015)

[16] Fentie M, Belete A, Mariam TG, J. Nanosci. Nanotechnol., 6, 262 (2015)

[17] Sivakumar T, Venkatesan P, Manavalan R, Valliappan K, J. Basic Clinical Pharmacy, 69(1), 154 (2007)

[18] Reddy AS, Sailaja AK, World J. Pharmacy Pharmaceutical Sci,, 3(6), 1781 (2014)

[19] Sudhakar P, Bhagyamma S, Siraj S, Sekharnath K, Rao K, Subha M, J. Appl. Pharm. Sci., 5(2), 51 (2015)

[20] Kianfar F, Antonijevic M, Chowdhry B, Boateng JS, Colloids Surf. B: Biointerfaces, 103, 99 (2013)

[21] Straccia MC, Ayal GG, Romano I, Oliva A, Laurienzo P, Marine Drugs., 13, 2890 (2015)

[22] Garud N, Garud A, Tropical J. Pharmaceutical Res., 11(4), 577 (2012)

[23] Pandey M, Amin MCIM, Ahmad N, Abeer MM, Int. J. Polym. Sci., 2013, 1 (2013)

[24] Ibrahim MM, Tamer Y, Fahmy A, Salaheldin EI, Mobarak F, Youssef MA, Mabrook MR, J. American Sci., 10(12), 108 (2014)

[25] Rodnyi PA, Khodyuk IV, Optics Spectroscopy, 111(5), 776 (2011)

[26] Soosen SM, Lekshmi B, George KC, SB Academic Review, 16(1&2), 57 (2009)

[27] Kumar H, Rani R, Int. Lett. Chem., Phys. Astronomy, 14, 26 (2013)

[28] Janotti A, Van de Walle CG, Reports on Progress in Physics, 72(126501), 29 (2009)

[29] Qin L, Shing C, Sawyer S, Dutta PS, Optical Mater., 33, 359 (2011)

[30] Pugachevskii MA, Technical Phys. Lett., 39(1), 36 (2013)

[31] Hammad TM, Salem JK, Harrison RG, Rev. Adv. Mater Sci., 22, 74 (2009)

[32] Egerton TA, Molecules, 19, 18192 (2011)

[33] Ano LMM, Stork CJ, Li YY, J. Cosmetic Dermatology, 9, 276 (2010)

[34] Salas C, Nypelo T, Rodriguez-Abreu C, Carrillo C, Rojas OJ, Curr. Opin. Colloid Interface Sci., 19, 383 (2014)

[35] Pal SB, Dutta J, Nanoscience Nanotechnology-Asia, 2, 90 (2012)

[36] Yang HY, Zhu SK, Pan N, J. Appl. Polym. Sci., 92(5), 3201 (2004)

[37] Nazir MS, Wahjoedi BA, Yussof AW, Abdulah MA, Bioresources, 8(2), 2161 (2013)

[38] Alemdar A, Sain M, Bioresour. Technol., 99(6), 1664 (2008)

[39] Saelee K, Yingkamhaeng N, Nimchua T, Sukyai P, The 26th Annual meeting of the Thai Society for Biotechnology and International Conference (2014).

[40] Morawski AW, Kusiak-Nejman E, Przepiorski J, Kordala R, Pernak J, Cellulose, 20, 1293 (2013)

[41] Galkina OL, Sycheva A, Blagodatskiy A, Kaptay G, Katanaev VL, Seisenbaeva GA, Kessler VG, Agafonov AV, J. Surf. Coat. Technol., 253, 171 (2014)

[42] Yu Q, Wu P, Li L, Liu T, Zhao L, Green Chem., 10, 1061 (2008)