Catalysis Letters, Vol.148, No.4, 1067-1072, 2018
Copper(I) Halide for Regioselective Ortho-Halogenation of Directed Arenes
We describe a copper(I) mediated halogenation via direct C-H functionalization of arenes. The combination of Cu(I)X and (diacetoxyiodo)benzene provides a robust system for halogenation of 2-arylpyridines. High regio- and mono-selectivity was achieved for chlorination, bromination, and iodination of arene C-H bonds. [GRAPHICS] .