To use the microwave/ML/TiO2 hybrid system as an advanced treatment of nitrobenzene (NB), a series of experiments were performed to examine the effects of microwave irradiation and auxiliary oxidants. The degradation of NB was carried out using different combinations of five-unit treatment techniques. The NB degradation rate increased with increasing microwave intensity. The circulation fluid velocity, concentration of H2O2, and the rate of O-2 gas injection showed the highest rate of degradation under optimal conditions. A significant synergistic effect was observed when H2O2 addition was combined with the microwave/ML/TiO2 hybrid process. (c) 2017 Elsevier B.V. All rights reserved.