Interpenetrating polymer network gel composed of poly(N-vinylacetamide) and poly(N-vinylisobutyramide) was designed for biomaterial use. Temperature triggered poly(N-vinylisobutylamide) (PNVIBA) moieties demonstrated character reversibility due to hydrophobic-hydrophilic change. In this study, the dynamic adsorption and desorption cycle property was determined by Rhodamine B.