Clathrate hydrates are icelike crystalline compounds with encaged guest molecules trapped inside the cages of hydrogen-bonded water molecules. Their growth is visualized for cyclopentane within water drops of 2 mu L on glass and polytetrafluoroethylene surfaces. The effect of the interfacial tension between water and cyclopentane is measured at different temperatures and for different concentrations of an oil-soluble surfactant, sorbitan monooleate (Span 80). The drops experience a temperature sequence where they freeze into ice, form hydrates, and melt. Cyclopentane hydrate crystals are affected by the concentration of the surfactant. The morphology seen here could be relevant for explaining the behavior of hydrate emulsions.