CuSbS2 is regarded as a promising photo-absorber for solar energy conversion due to its proper bandgap, high absorptivity and earth abundance. Herein, novel low-cost ZnO/CdS/CuSbS2 core-shell nanowire arrays were constructed as photoanode for hydrogen evolution through non-aqueous electrodeposition and cation exchange. The nanowire demonstrates even and compact multilayer structure. The optimal ZnO/CdS/CuSbS2 photoanode achieves a photocurrent of 6.48 mA/cm(2) at 0 V versus Ag/AgCI and the remarkable IPCE value with approximately 52% at 480 nm in an electrolyte solution containing 0.35 mol/L Na2SO3 and 0.25 mol/L Na2S. It also exhibited a good stability, maintained 87.9% of the initial current after 1 h measurement. The high performance benefits from well-crystalline and compact multilayer structure, high absorptivity of CuSbS2 and CdS, p-n junction formed between CdS and CuSbS2 which promotes the electron-hole separation and ZnO nanowire array as three dimensional scaffolds for electron percolation pathway. This work suggests the potential applications of low-cost p-n junction core-shell nanowire arrays as a highly efficient photoanode for hydrogen evolution in oil-field waste water with reductive sulfide. (C) 2018 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.