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Journal of Polymer Science Part A: Polymer Chemistry, Vol.56, No.6, 672-680, 2018
A water-soluble, AIE-active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells
A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water-soluble and exhibits aggregation-induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells, providing useful information of cellular morphology and intracellular aggregation or motion. (c) 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 672-680
Keywords:aggregation-induced emission;cellular morphology;conjugated polyelectrolyte;fluorescence lifetime imaging;water-soluble