Polypyrrole (PPy) films containing heparin (Hep), salicylate (Sa) or both anions were electrochemically deposited as single layers or bilayers onto Nitinol (NiTi) alloy. The PPy deposition onto the bare alloy was achieved through an anodic electropolymerization in the presence of the anions. The aim of this study was to determine the influence of the electrosynthesis parameters (electrolyte nature and monomer and electrolyte concentrations) on the electroforming mechanism and morphology of the PPy. The PPy coating containing Hep and Sa not only presents a very good anticoagulant activity but also presents excellent anticorrosive properties in Ringer's solution. (C) 2018 Elsevier B.V. All rights reserved.