A novel surfactant 2-((2-(decyloxy)ethyl)amino)lauric acid (LDEA) - substituting 3-(decyloxy)propan-l-amine (DPA) on the alpha-carbon position of lauric acid was firstly synthesized and utilized as a collector for the flotation of quartz mineral at a relatively low temperature. The flotation performances and adsorption mechanisms of LDEA collector on quartz mineral surface were investigated by zeta potential measurements, Fourier transform infrared (FT-IR) spectroscopy, and X-ray photoelectron spectroscopy (XPS), in conjunction with the results of quartz micro-flotation tests. The flotation results showed that LDEA exhibited an excellent collecting performance on quartz mineral at a wide pulp pH range (about 6-11) with a low collector concentration 15.0 mg/L at a relatively low temperature 15 degrees C, where above 95.0% of the quartz mineral could be floated. Zeta potential measurements, FT-IR spectra, and XPS analyses reveal that the LDEA collector could be adsorbed on the surface of pure quartz in the forms of electrostatic and hydrogen bonding interactions at pulp pH 10.0.