For enhancing the thermal performance of the crystallizer cooling water and also to achieve stable and uniform suspension,TiO2 nanoparticle modified with (3-mercaptopropyl) triethoxysilane (MPS) coupled Ag nanopartide was added to the cooling water. Other than the investigation on the thermal performance, rheological properties were also investigated, both prior and post nanoparticle addition. The XRD, FT-IR spectrometer and TEM were used to study the morphology and properties of TiO2-Ag nanoparticles. Simultaneously, UV-vis absorption spectrometer and zeta potential were used to confirm the stability of the prepared nanofluids. Furthermore, the temperature dependent thermal conductivity study with different volume fractions carried out for TiO2-Ag cooling water-based nanofluids reported considerable enhancement. Based on researching rheological property, TiO2-Ag nanofluids are found to be promising to the research of crystallization cooling water. Moreover, experiment results have been compared with classical models and new formulas were rebuilt for thermal conductivity and viscosity. This study will play a significant role in the study of the heat transfer of crystallizer cooling water. (C) 2017 Elsevier B.V. All rights reserved.