The work is focused on the investigation of the influence of ternary metal oxide promoted ceria based materials (Cu-Mn-Zr-Ce-O) with various Cu/Mn molar ratios on the physicochemical and catalytic properties for CO oxidation in model reaction. It is shown that no diffraction peaks corresponding to coper and/or manganese oxides were indicated, ensuring the formation of solid solution based on ceria. The crystallite size of all samples is about 7-9 nm, and did not depend on the Cu/Mn ratio. The optimum catalyst composition was Cu0.08Mn0.02(Zr-0.1)Ce0.9O2. To understand the feature of this optimum catalyst composition the investigation of structure and morphological characterization by XRD, TEM, HR TEM, TG-DSC, FTIR, Raman, and XPS of samples was carried out.