Sodium alginate and Poly vinyl alcohol (PVA) based scaffolds are very well used for wound healing purpose. Sodium alginate is a natural polymer which is used for many biomedical applications. PVA is a biocompatible polymer used in many biomedical applications. Incorporation of Titanium dioxide (TiO2) nanoparticles in the scaffold increases the wound healing property of the scaffold. TiO2 nanoparticles are biocompatible. They enhance the wound healing activity by photo catalytic property. Curcumin is used for the treatment of inflammation. It is the main active compound of turmeric Curcumin is used for treatment of wound and inflammation. It had antimicrobial and antioxidant property. (C) 2018 Elsevier B.V. All rights reserved.