Monomers with leucine-tyrosine linkages were synthesized using diphenyl phosphoryl azide as a coupling reagent. Leucyltyrosylpoly(propylene glycol) bis(2-aminopropyl ether) tyrosylleucine (monomer 1) has a longer spacer : poly(propylene glycol) bis(2-aminopropyl ether (Jeffamine(R) D-400), and leucyltyrosyliminohexamethyleneiminotyrosylleucine (monomer 2) has a shorter spacer : hexamethylenediamine. Polyureas from monomers 1 and 2 with hexamethylene diisocyanate and methylenedi-p-phenyl diisocyanate were synthesized. Polyamide, polyesteramide from monomer 2 were synthesized. The characterization of these polymers using H-1-NMR, C-13-NMR, solid-state C-13-NMR, IR, GPC, and also thermal analysis are presented.