We solve a model reference adaptive control problem for a class of linear 2 x 2 hyperbolic partial differential equations (PDEs) with uncertain system parameters subject to harmonic disturbances, from a single boundary measurement anticollocated with the actuation. This is done by transforming the system into a canonical form, from which filters are designed so that the states can be expressed as linear combinations of the filters and uncertain parameters, a representation facilitating for the design of adaptive laws. A stabilizing controller is then combined with the adaptive laws to make the measured signal asymptotically track the output of a reference model. The reference model is taken as a simple transport PDE. Moreover, pointwise boundedness of all variables in the closed loop is proved, provided the reference signal is bounded. The theory is demonstrated in a simulation.